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Background Information:
AZD4547 is a potent, selective and orally active pan-FGFR inhibitor, with IC50s of 0.2, 2.5, 1.8 and 165 nM for FGFR1, 2, 3 and 4, respectively.
APIM050097: AZD4547
CAS No.: 1035270-39-3.
Molecular Formula: C26H33N5O3 ? 0.2HCl ? 0.4H2O.
Molecular Weight: 478.1.
Purity: >99% purity (HPLC at 214 and 254 nm).
QC: HPLC, 1HNMR and quantitative microanalysis.
Solubility: In DMSO, water with 1 eq. of acid.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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