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Background Information:
A potent and highly selective antagonist of A2b adenosine receptor (A2bAR) with a Ki of 8.3 nM, differentiating from other adenosine receptors, such as A1 (~10,000 nM), A2a (>10,000 nM) and A3 (>>10,000 nM).
Reference:
1. Chun-Xiao Sun, et al, The Journal of Clinical Investigation (August 2006) 116 (8), 2173-2182; 2. Jacobson KA, et al," Nature reviews. Drug discovery (2006) 5 (3), 247-64.
APIM050271: CVT-6883
CAS No.: 752222-83-6.
Molecular Formula: C21H21F3N6O2.
Molecular Weight: 446.4.
Purity: >98.5% (HPLC).
QC: MS (EI), 1HNMR, HPLC.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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