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GH Protein

Growth Hormone, GH-N, hGH-N

Catalog No. Product Name Size List Price (US$) Quantity
BP000202-CYT-297 Recombinant Carp Growth Hormone 50 ug 160.00
BP000202-CYT-297 Recombinant Carp Growth Hormone 1 mg 2100.00
Description

Introduction
GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus.

BP000202-CYT-297: Recombinant Carp Growth Hormone

Source: E.Coli-derived.
Predicted molecular mass: 21,408 Dalton.
N-terminal sequence analysis: Ser-Asp-Asn-Gln-Arg.
Carp GH is biologically active in rat 3T3 F442A preadipocytes, though its activity is 15-fold lower compared to bovine GH, but it is equally potent in vivo in promoting carp growth (Fine et al.1993). Furthermore, carp GH forms 1:2 complex with the extra cellular domain of ovine growth hormone receptor.
Purity > 95.0% as determined by RP-HPLC and SDS-PAGE.
Formulation:The GH Carp was lyophilized from a concentrated (1 mg/ml) solution with 0.3% NaHCO3 adjusted to pH 8.
Reconstitution: It is recommended to reconstitute the lyophilized Growth Hormone Carp recombinant in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

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