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GH Protein

Growth Hormone, GH-N, hGH-N

Catalog No. Product Name Size List Price (US$) Quantity
BP000202-CYT-636 Recombinant Bovine Growth Hormone 100 ug 160.00
BP000202-CYT-636 Recombinant Bovine Growth Hormone 1 mg 525.00
Description

Introduction
GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus.

BP000202-CYT-636: Recombinant Bovine Growth Hormone

Source: E.coli-derived.
A single, non-glycosylated polypeptide chain containing 191 amino acids and having a molecular mass of 21.8 kDa.
N-terminal sequence analysis: Ala-Thr-Phe-Pro-Ala.
The activity as determined by the PDFP13B9 cells stably transfected with rabbit GH receptors. Bovine GH is also capable of forming a 1:2 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD).
Purity: > 98.0% as determined by SEC-HPLC and SDS-PAGE.
Formulation: The Bovine Growth Hormone protein was lyophilized from a concentrated (1 mg/ml) solution with 0.0045 mM NaHCO3 adjusted to pH-8.
Reconstitution: It is recommended to reconstitute the lyophilized Bovine Growth Hormone in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

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