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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal MCP 1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. This chemokine is produced as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide, with a molecular weight of approximately 13 kDa. As with many other CC chemokines, CCL2 is located on chromosome 17 in humans. The cell surface receptors that bind CCL2 are CCR2 and CCR5.
BP000275-CHM-315: Recombinant Rat MCP-1 (CCL2)
Source: E. coli-derived.
N-terminal sequence analysis: Gln-Pro-Asp-Ala-Val.
A non-glycosylated, Polypeptide chain containing 125 amino acids and having a molecular mass of 14 kDa.
ED50 =1-10 ug/ml corresponding to a Specific Activity of 10,000-100,000 IU/mg. The biological activity was determined by measuring the dose dependent chemotaxis with human THP-1 cells. The optimal concentration should be determined for each specific application by an initial dose-response assay.
Purity > 95%, by SDS-PAGE.
Formulation: Lyophilized from a concentrated (1 ug/ml) sterile solution containing no additives.
Reconstitution: It is recommended to reconstitute the lyophilized Monocyte Chemotactic Protein-1 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other MCP 1 Proteins:
Recombinant Human MCP-1 (CCL2)
Recombinant Mouse MCP-1 (CCL2)
Recombinant Human MCP-1 (CCL2), His Tag
MCP-1 Antibodies:
MCP-1 Polyclonal Antibody
MCP 1 Monoclonal Antibody
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